Silpe, Justin

Education

Bachelor of Arts

University of Michigan, 2012

Masters of Science

University of Michigan, 2013

About this team member

Justin Silpe started as a  third year undergraduate pursuing an individual concentration program in “Theoretical Medicine & Bioethics”. He began his work under Dr. Seok Ki Choi at the Michigan Nanotechnology Institute for Medicine and Biological Sciences studying the release kinetics of a photolabile linker exposed to varying wavelengths and pH environments.  Justin continued to work with Dr. Choi  and the Banaszak Holl lab on SPR binding studies of precisely defined folate and methotrexate ligands as part of his research for the Master’s degree in Macromolecular Science and Engineering.

Publications

  • Avidity Mechanism of Dendrimer-Folic Acid Conjugates Molecular Pharmaceutics 2014 11 1696-1706
  • Poly(amidoamine) Dendrimer-Methotrexate Conjugates: The Mechanism of Interaction with Folate Binding Protein Molecular Pharmaceutics 2014 11 4049-4058
  • Dendrimer-Based Multivalent Vancomycin Nanoplatform for Targeting the Drug-Resistant Bacterial Surface ACS Nano 2013 7 214-228
  • Avidity Modulation of Folated-Targeted Multivalent Dendrimers for Evaluating Biophysical Models of Cancer Targeting Nanoparticles ACS Chemical Biology 2013 8 2063-2071