Drug and Gene Delivery

Force Spectroscopy of Multivalent Binding of Riboflavin-Conjugated Dendrimers to Riboflavin Binding Protein A Leistra, J. Han, S. Tang, B. G. Orr, M. M. Banaszak Holl, S. K. Choi, K. Sinniah Journal of Physical Chemistry B 2015 119 5785-5792
Quantitative Measurement of Cationic Polymer Vector and Polymer-pDNA Polyplex Intercalation into the Cell Plasma Membrane S. Vaidyanathan, K. B. Anderson, R. L. Merzel, B. Jacobovitz, M. P. Kaushik, C. N. Kelly, M. A. van Dongen, C. A. Dougherty, B. G. Orr, and M. M. Banaszak Holl ACS Nano 2015 9 6097-6109
See: Anderson, Kevin Dougherty, Casey Kaushik, Milan Merzel, Rachel Nieh, Christina Vaidyanathan, Sriram van Dongen, Mallory
Generation 3 PAMAM Dendrimer TAMRA Conjugates Containing Precise Dye/Dendrimer Ratios J. Manono, C. A. Dougherty, K. Jones, J. DeMuth, M. M. Banaszak Holl, S. DiMaggio Materials Today Communications 2015 4 86-92
See: Stassi DiMaggio Dougherty, Casey
G5-PEG PAMAM dendrimer incorporating nanostructured lipid carriers enhance oral bioavailability and plasma lipid-lowering effect of probucol R. Qi, Y. Z. Li, C. Chen, Y. N. Cao, M. M. Yu, L. Xu, B. He, X. Jie, W. W. Shen, Y. N. Wang, M. A. van Dongen, G. Q. Lui, M. M. Banaszak Holl, Q. Zhang, X. Ke Journal of Controlled Release 2015 210 160-168
See: Rong Qi van Dongen, Mallory
High-resolution NMR characterization of low abundance oligomers of amyloid-beta without purification S. Kotler, J. Brender, S. Vivekanandan, Y. Suzuki, K. Yamamoto, M. Monette, J. Krishnamoorthy, P. Walsh, M. Cauble, M. M. Banaszak Holl, E. N. G. Marsh, A. Ramamoorthy Scientific Reports 2015 5 11811
See: Cauble, Meagan
Characterization of Folic Acid and Poly(amidoamine) Dendrimer Interactions with Folate Binding Protein: A Force-Pulling Study P.R. Leroueil, S. DiMaggio, A. N. Leistra, C. D. Blanchette, C. Orme, K. Sinniah, B. G. Orr, and M. M. Banaszak Holl Journal of Physical Chemistry B 2015 119 11506-11512
See: Stassi DiMaggio Leroueil, Pascale
G5 PAMAM dendrimer versus liposome: A comparison study on the in vitro transepithelial transport and in vivo oral absorption of simvastatin Q. Rong, H. R. Zhang, L. Xu, W.W. Shen, C. Chen, C. Wang, Y. N. Cao, Y. A. Wang, M. A. van Dongen, B. He, S. L. Wang, G. Liu, M. M. Banaszak Holl, Q. Zhang. Nanomedicine - Nanotechnology, Biology, and Medicine 2015 11 1141-1151
See: van Dongen, Mallory
Detergent Induction of HEK 293A Cell Membrane Permeability Measured under Quiescent and Superfusion Conditions Using Whole Cell Patch Clamp S. Vaidyanathan, B. G. Orr. M. M. Banaszak Holl Journal of Physical Chemistry B 2014 118 2112-2123
See: Vaidyanathan, Sriram
Isolation and Characterization of Precise Dye/Dendrimer Ratios C. A. Dougherty, J. C. Furgal, M. A. van Dongen, T. Goodson, M. M. Banaszak Holl, J. Manono, S. DiMaggio Chemistry a European Journal 2014 20 4638-4645
See: Stassi DiMaggio Dougherty, Casey van Dongen, Mallory
Avidity Mechanism of Dendrimer-Folic Acid Conjugates MA van Dongen, JE Silpe, CA Dougherty, AK Kanduluru, SK Choi, BG, Orr, PS Low, MM Banaszak Holl Molecular Pharmaceutics 2014 11 1696-1706
See: Seok-ki Choi Dougherty, Casey Silpe, Justin van Dongen, Mallory
Quantification of cytosolic plasmid DNA degradation using high-throughput sequencing: implications for gene delivery R. Rattan, A.U. Bielinska, M. M. Banaszak Holl Journal of Gene Medicine 2014 16 75-83
See: Rattan, Rahul
Diffusion NMR Study of Generation-Five PAMAM Dendrimer Materials M. A. van Dongen, B. G. Orr, and M. M. Banaszak Holl Journal of Physical Chemistry B 2014 118 7195-7202
See: van Dongen, Mallory
Multivalent Polymers for Drug Delivery and Imaging: The Challenges of Conjugation M. A. van Dongen, C. A. Dougherty, M. M. Banaszak Holl Biomacromolecules 2014 15 3215-3234
See: Dougherty, Casey van Dongen, Mallory
Hyperspectral imaging and characterization of live cells by broadband coherent anti-Stokes Raman scattering (CARS) microscopy with singular value decomposition (SVD) analysis. A. Khmaladze, J. Jasensky, E. Price, C. Zhang, A. Boughton, X. Han, E. Seeley, X. Liu, M. M. Banaszak Holl, Z. Chen Applied Spectroscopy 2014 68 1116-1122
See: Price, Erika
Poly(amidoamine) Dendrimer-Methotrexate Conjugates: The Mechanism of Interaction with Folate Binding Protein M. A. van Dongen, R. Rattan, J. Silpe, C. Dougherty, N. L. Michmerhuizen, M. Van Winkle, B. Huang, S.-K. Choi, K. Sinniah, B.G. Orr, M. M. Banaszak Holl Molecular Pharmaceutics 2014 11 4049-4058
See: Dougherty, Casey Rattan, Rahul Silpe, Justin van Dongen, Mallory
The role of caveolin-1 and syndecan-4 in the internalization of PEGylated PAMAM dendrimer polyplexes into myoblast and hepatic cells W.W. Shen, M. A. van Dongen, Y.C. Han, M. M. Yu, Y. Z. Li, G. Liu, M. M. Banaszak Holl, R. Qi. European Journal of Pharmaceutics and Biopharmaceutics 2014 88 658-663
See: van Dongen, Mallory
Dendrimer-Based Multivalent Vancomycin Nanoplatform for Targeting the Drug-Resistant Bacterial Surface S.K Choi, A. Myc, J.E. Silpe, M. Sumit, P.T. Wong, K. McCarthy, A.M. Desai, T.P. Thomas, A. Kotlyar, M. M. Banaszak Holl, B. G. Orr, J.R. Baker ACS Nano 2013 7 214-228
See: Seok-ki Choi Silpe, Justin
Attractive Hydration Forces in DNA-Dendrimer Interactions on the Nanometer Scale M. Mills, B. G. Orr, M. M. Banaszak Holl, I. Andricioaei Journal of Physical Chemistry B 2013 117 973-981
Polyplex Exposure Inhibits Cell Cycle, Increases Inflammatory Response, and Can Cause Protein Expression without Cell Division R. L. Matz, B Erickson, S. Vaidyanathan, J. F. Kukowska-Latallo, J. R. Baker, B. G. Orr, and M. M. Banaszak Holl Molecular Pharmaceutics 2013 10 1306-1317
See: Erickson, Blake Matz, Becky Vaidyanathan, Sriram
Quantitative analysis of generation and branch defects in G5 poly(amidoamine) dendrimer M. A. van Dongen, A. Desai, B. G. Orr, J. R. Baker, M. M. Banaszak Holl Polymer 2013 54 4126-4133
See: van Dongen, Mallory