Drug and Gene Delivery

  • Polyplex-Induced Cytosolic Nuclease Activation Leads to Differential Transgene Expression Molecular Pharmaceutics 2013 10 3013-3022
    See: Rattan, RahulShakya, AnishaVaidyanathan, Sriram
  • Epithelial-Mesenchymal Transition Enhances Nanoscale Actin Filament Dynamics of Ovarian Cancer Cells Journal of Physical Chemistry B 2013 117 9233-9240
  • PAMAM Dendrimers as Quantized Building Blocks for Novel Nanostructures Soft Matter 2013 9 11188-11196
    See: Vaidyanathan, Sriramvan Dongen, Mallory
  • Avidity Modulation of Folated-Targeted Multivalent Dendrimers for Evaluating Biophysical Models of Cancer Targeting Nanoparticles ACS Chemical Biology 2013 8 2063-2071
    See: Silpe, Justinvan Dongen, Mallory
  • Bifunctional PAMAM Dendrimer Conjugates of Folic Acid and Methotrexate with Defined Ratio Biomacromolecules 2012 13 982-991
    See: Lee, Kyung-hoon
  • Dendrimer-Based Nanoparticle Therapies: Can Uniform Multifunctional Therapeutics Be Made with Current Chemical Approaches? 2012
    See: McNerny, DanMullen, Douglas
  • Cell Volume Changes During Apoptosis Monitored in Real Time Using Digital Holographic Microscopy Journal of Structural Biology 2012 178 270-278
    See: Matz, Becky
  • Dual-wavelength digital holographic imaging with phase background subtraction Optical Engineering 2012 51 55801
    See: Matz, Becky
  • Best Practices for Purification and Characterization of PAMAM Dendrimer Macromolecules 2012 45 5316-5320
    See: Barash, MarkMullen, Douglasvan Dongen, Mallory
  • Efficient in vitro siRNA delivery and Intramuscular Gene Silencing using PEG-Modified PAMAM Dendrimers Molecular Pharmaceutics 2012 9 1812-1821
    See: Rong Qivan Dongen, Mallory
  • Intrinsic Dynamics of DNA-Polymer Complexes: A Mechanism for DNA Release Molecular Pharmaceutics 2012 9 2743-2749
    See: Prevette, Lisa
  • Dendrimer-based multivalent methotrexates as dual acting nanoconjugates for cancer cell targeting. European Journal of Medicinal Chemistry 2012 47 560-572
    See: Lee, Kyung-hoon
  • Effect of pH and Generation on Structural Properties of Poly(amidoamine) Dendrons Studied by Molecular Dynamics Simulations Journal of Computational and Theoretical Nanoscience 2012 9 122-126
    See: Lee, Kyung-hoon
  • Biophysical Characterization of a Riboflavin-Conjugated Dendrimer Platform for Targeted Drug Delivery Biomacromolecules 2012 13 507-516
    See: Seok-ki Choi
  • Dual-wavelength linear regression phase unwrapping in three-dimensional microscopic images of cancer cells Optics Letters 2011 36 912-914
    See: Matz, Becky
  • Acetonitrile Shortage: Use of isopropanol as an alternative elution system for ultrahigh performance liquid chromatograph Analytical Methods 2011 3 56-58.
    See: Mullen, Douglas
  • Polyvalent saccharide-functionalized generation 3 poly(amidoamine) dendrimer-methotrexate conjugate as a potential anticancer agent. Bioorganic & Medicinal Letters 2011 19 2557-2564
    See: Lee, Kyung-hoon
  • Design, Synthesis, and Biological Functionality of a Dendrimer-based Modular Drug Delivery Platform Bioconjugate Chemistry 2011 22 679-689
    See: Stassi DiMaggioKelly, ChristopherMcNerny, DanMullen, Douglas
  • Bioanalytical Screening of Riboflavin Antagonists for Targeted Drug Delivery-A Thermodynamic and Kinetic Study ACS Medicinal Chemistry Letters 2011 2 363-367
    See: Seok-ki Choi
  • Heterogeneous ligand-nanoparticle distributions: a major obstacle to scientific understanding and commercial translation Accounts of Chemical Research 2011 44 1135-1252
    See: Mullen, Douglas