Leroueil, Pascale


Bachelor of Science
Whitman College, 2003


About this team member

Pascale graduated from Whitman College in 2003 and obtained her PhD in 2008. Her research focused on the interactions of polymeric nanoparticles with biological membranes. She is a staff scientist with the Michigan Nanotechnology Institute for Medicine and Biological Sciences.

Pascale’s paper in Bioconjugate Chemistry 2006, 17,728-734 was selected as one of the top 25 “best Articles and Communications from the first 25 years of BC, highlighting the breadth of science and impact of the journal.”


  • Characterization of Folic Acid and Poly(amidoamine) Dendrimer Interactions with Folate Binding Protein: A Force-Pulling Study Journal of Physical Chemistry B 2015 119 11506-11512
  • Stoichiometry and Structure of Poly(amidoamine) Dendrimer-Lipid Complexes ACS Nano 2009 3 1886-1896.
  • Wide Varieties of Cationic Nanoparticles Induce Defects in  Supported Lipid Bilayers Nanoletters 2008 8 420-424
  • Poly(amidoamine) dendrimers on lipid bilayers I: Free energy and conformation of binding Journal of Physical Chemistry B 2008 112 9339-9345
  • Poly(amidoamine) dendrimers on lipid bilayers II: Effects of bilayer phase and dendrimer termination Journal of Physical Chemistry B 2008 112 9346-9353
  • Interaction of Poly(amidoamine) Dendrimers with Survanta Lung Surfactant:  The Importance of Lipid Domains Langmuir 2008 24 11003-11008
  • Nanoparticle Interaction with Biological Membranes:  Does Nanotechnology Present a Janus Face? Accounts of Chemical Research 2007 40 335-342
  • Nanoparticle-Membrane Interaction: Mechanism for Enhanced Permeability 2007
  • Interaction of Polycationic Polymers with Supported Lipid Bilayers and Cells: Nanoscale Hole Formation and Enhanced Membrane Permeability. Bioconjugate Chemistry 2006 17 728-734.
  • Physical Interactions of Nanoparticles with Biological Membranes:The Observation of Nanoscale Hole Formation. Chemical Health and Safety 2006 13 16-20.