Drug and Gene Delivery

Evaluation of a symmetry-based strategy for assembling protein complexes D. P. Patterson, A. M. Desai, M. M. Banaszak Holl, E. N. G. Marsh RSC Advances 2011 1 1004-1012
The Mechanism of Polyplexes Internalization into Cells: Testing the GM1/Caveolin-1-Mediated Lipid Raft Mediated Endocytosis Pathway R. Qi, D. Mullen, J. R. Baker, M. M. Banaszak Holl Molecular Pharmaceutics 2010 7 267-279.
See: Mullen, Douglas Rong Qi
A Quantitative Assessment of Nanoparticle-Ligand Distributions: Implications for Targeted Drug and Imaging Delivery in Dendrimer Conjugates D. G. Mullen, M. Fang, A. M. Desai, J. R. Baker, B. G. Orr, and M. M Banaszak Holl ACS Nano 2010 4 657-670.
See: Fang, Ming (Flora)Mullen, Douglas
Microscopic Basis for the Mesoscopic Extensibility of Dendrimer-Compacted DNA M. Mills, B. G. Orr, M. M. Banaszak Holl, and I. Andricioaei Biophysical Journal 2010 98 834-842
Polycation-Induced Cell Membrane Permeability Does Not Enhance Cellular Uptake or Expression Efficiency of Delivered DNA L. Prevette, D. Mullen, M. M. Banaszak Holl Molecular Pharmaceutics 2010 7 870-883.
See: Mullen, Douglas Prevette, Lisa
Solid State NMR Reveals the Hydrophobic-Core Location of Poly(amidoamine) Dendrimers in Biomembranes P. Smith, J. Brender, U. Durr, J. Xu, D. Mullen, M. M. Banaszak Holl, A Ramamoorthy J. Am. Chem. Soc. 2010 132 8087-8097.
See: Mullen, Douglas
Effect of Mass Transport in the Synthesis of Partially Acetylated Dendrimer: Implications for Functional Ligand-Nanoparticle Interactions D. G Mullen, E. L. Borgmeier, M. Fang, D. Q. McNerny, A. Desai, J. R. Baker, B. G. Orr, M. M. Banaszak Holl Macromolecules 2010 43 6577-6587.
See: Borgmeier, Emilee Fang, Ming (Flora)McNerny, Dan Mullen, Douglas
Isolation and Characterization of Dendrimers with Precise Numbers of Functional Groups D. G Mullen, E. L. Borgmeier, A. Desai, M. A. Van Dongen, M. Barash, X.-M. Chen, J. R. Baker, B. G. Orr, M. M. Banaszak Holl Chemistry a European Journal 2010 10 10675-10678.
See: Barash, Mark Borgmeier, Emilee Mullen, Douglas van Dongen, Mallory
Origin of broad polydispersion in functionalized dendrimers and its effects on cancer-cell binding affinity J. N. Waddell, D. G. Mullen, B. G. Orr, M. M. Banaszak Holl, L. M. Sander Physical Review E 2010 82 36108
See: Mullen, Douglas
Nanotoxicology: a personal perspective 2009
Development of a remanence measurement-based SQUID system with in-depth resolution for nanoparticle imaging S. Ge, X. Shi, J. R. Baker, M. M. Banaszak Holl, B. G. Orr Physics in Medicine and Biology 2009 54 N177-N188
See: Ge, Song
Stoichiometry and Structure of Poly(amidoamine) Dendrimer-Lipid Complexes C. V. Kelly, M. G. Liroff, L. D. Triplett, P. R. Leroueil, D. G. Mullen, J. M. Wallace, S. Meschinchi, J. R. Baker, B. G. Orr, M. M. Banaszak Holl ACS Nano 2009 3 1886-1896.
See: Triplett, Devon Kelly, Christopher Leroueil, Pascale Liroff, Meghan Mullen, Douglas Wallace, Joseph
Pulsed-laser creation and characterization of giant plasma membrane vesicles from cells C. V. Kelly, M.-M. Kober, P. Kinnunen, D. A. Reis, B. G. Orr, M. M. Banaszak Holl Journal of Biological Physics 2009 35 279-295.
See: Kelly, Christopher Kober, Maggie
Cationic Nanoparticles Induce Nanoscale Disruption in Living Cell Plasma Membranes J. Chen, J. A. Hessler, K. Putchakayala, B. K. Panama, D. P. Khan, S. Hong, D. G. Mullen, S. C. DiMaggio, A. Som, G. N. Tew, A. N. Lopatin, J. R. Baker, M. M. Banaszak Holl, B. G. Orr Journal of Physical Chemistry B 2009 113 11179-11185
See: Chen, Jiumei Stassi DiMaggio Hessler, Jessica Hong, Seungpyo Khan, Damian Mullen, Douglas
The Role of Ganglioside GM1 in Cellular Internalization Mechanisms of Poly(amidoamine) Dendrimers S. Hong, R. Rattan, I. Majoros, D. G. Mullen, J. L. Peters, X. Shi, A. U. Bielinska, L. Blanco, B. G. Orr. J. R. Baker, M. M. Banaszak Holl Bioconjugate Chemistry 2009 20 1503-1513.
See: Hong, Seungpyo Mullen, Douglas Rattan, Rahul
Facile Hydrothermal Synthesis of Iron Oxide Nanoparticles with Tunable Magnetic Properties S. Ge, X. Shi, K. Sun, C. Li, C. Uher, J. R. Baker, M. M. Banaszak Holl, B. G. Orr J. Phys. Chem. C. 2009 113 13593-13599
See: Ge, Song
RGD Dendron Bodies: Synthetic Avidity Agents with Defined and Potentially Interchangeable Effector Sites That Can Substitute for Antibodies D. Q. McNerny, J. F. Kukowska-Latallo, D. G. Mullen, J. M. Wallace, A. M.Desai, R. Shukla, B. Huang, M. M. Banaszak Holl, J. R. Baker Bioconjugate Chemistry 2009 20 1853-1859.
See: McNerny, Dan Mullen, Douglas Wallace, Joseph
Cationic Poly(amidoamine) Dendrimer Induces Lysosomal Apoptotic Pathway at Therapeutically Relevant Concentrations T. P. Thomas, I. Majoros, A. Kotlyar, D. Mullen, M. M. Banaszak Holl and J. R. Baker Biomacromolecules 2009 10 3207–3214.
See: Mullen, Douglas
Wide Varieties of Cationic Nanoparticles Induce Defects in Supported Lipid Bilayers P. R. Leroueil, S. A. Berry, K. Duthie, G. Han, V. M. Rotello, D. Q. McNerny, J. R. Baker, Jr.; B. G. Orr, M. M. Banaszak Holl Nanoletters 2008 8 420-424
See: Berry, Stephanie Duthie, Kristen Leroueil, Pascale McNerny, Dan
Synthesis, Characterization, and In Vitro Testing of Superparamagnetic Iron Oxide Nanoparticles Targeted Using Folic Acid-Conjugated Dendrimers K. J. Landmark, S. C. DiMaggio, J. Ward, C. V. Kelly, S. Vogt, S. Hong, A. Kotlyar, J. E. Penner-Hahn, J. R. Baker, Jr., M. M. Banaszak Holl, B. G. Orr ACS Nano 2008 2 773-783
See: Stassi DiMaggio Hong, Seungpyo Kelly, Christopher Landmark, Kevin